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| Doppler Index of Ovarian Stromal Artery: Clinical Significance as a Predictor of Ovarian Response and Pregnancy in Controlled Ovarian Hyperstimulation for In Vitro Fertilization and Embryo Transfer |
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| Seok Hyun Kim, M.D.*, Seung Yup Ku, M.D., Byung Chul Jee, M.D.*, Chang Suk Suh, M.D.*, Young Min Choi, M.D.*, Jung Gu Kim, M.D., Shin Yong Moon, M.D.*, Jin Yong Lee, M,D. |
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| Department of Obstetrics and Gynecology, College of Medicing, Institute of Reproductive Medicine adn Population, Medical Research Center*, Seoul National University, Seoul, Korea |
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| PURPOSE : To assess whether the doppler index of ovarian stromal artery predicts the outcomes of controlled ovarian
hyperstimulation (COH) for in vitro fertilization and embryo transfer (IVF-ET) such as ovarian response and
pregnancy.
MATERIALS and METHODS : Pulsatility index (PI) was measured using transvaginal Doppler ultrasonography in 99 infertile
patients undergoing IVF-ET. PI was obtained from bilateral ovarian stromal arteries on the starting day of
COH (PI1) and the day of hCG administration (PI2). The outcomes of IVF-ET were analyzed and correlated
with PI values.
RESULTS : Patients were divided into three groups using PI1 of 1.3 and 2.3, PI2 of 1.0 and 2.0, and ΔPI (PI2-PI1) of
0.2 and 0.4, respectively. There were no significant differences in the outcomes of COH among three groups.
The pregnancy rate was significantly higher in group of PI1 value below 1.3 (61.4%) than in group of PI1 value
above 2.3 (33.3%), in group of PI2 value below 1.0 (61.0%) than in group of PI2 value above 2.0 (34.3%), and in
group of ΔPI value below 0.2 (60.0%) than in group of ΔPI value above 0.4 (34.1%) (p<0.05). Significant
positive correlations were found between PI1 or PI2 and total dosage of gonadotropins for COH
(Y=0.483X+27.1, r=0.052, p<0.05; Y=0.877X+26.6, r=0.075, p<0.05).
CONCLUSION : The lower PI of ovarian stromal artery during COH, the higher the pregnancy rate and the smaller the
amount of gonadotropin was needed for effective COH. This study suggests that the pulsatility index of ovarian
stromal artery during COH may be useful in predicting the success of IVF-ET. |
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| Keyword : Infertility; In vitro fertilization and embryo transfer(IVF-ET); Controlled ovarian hyperstimulation(COH); Ovary; Ultrasound(US), Doppler studies |
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pdf파일 : K20200049.pdf 
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> Journal > Journal Search 
Journal of Korean Society of Ultrasound in Medicine 2001 ; 20 (1) : p.49 - 59
